$node = new stdClass();
$node->title = 'Node title';
$node->body = 'Node body';
$node->type = 'book';
$node->uid = 1;
$node->filter = 1;
$node->status = 1;
$node->comment = 2;
$node->field_publisher[0]['value'] = 'Foo'; // текстовое cck поле field_publisher
$node->field_author[0]['value'] = 'Bar';    // текстовое cck поле field_author
 
node_save($node);

Drupal 6.x